Archives: Research Articles
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Plasmodium falciparum
Supplementary files and notes of the manuscript Pramanik et al., 2020: Proteomic Atomics Reveals a Distinctive Uracil-5-Methyltransferase Figure: Proteome-based atom (C, H, N, O, S) distributions across all species of the phylogenetic tree revealed U5MTase of Plasmodium falciparum as a distinguished possible therapeutic target which in turn was used for in silico structure-based drug design…
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Taxonomy Driven Gene Prediction
Introduction Gene predication is an important technique of modern genetics for inferring structure and extension of genes from existing genome data, i.e. DNA level information. It is vital for postulating gene orthologs in the case that there are no laboratory sequenced gene information (e.g. mRNA). The orthologs of a given gene G can be used…
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Clustering for Taxonomically Ordered Matrices
Your data are represented in form of a matrix? X-axis as well as Y-axis of this matrix are somehow equally ordered? Further you know that the data within your matrix are the less related to each other the more distant they are with respect to the involved order. Then have a look to the two…
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p48ZnF mouse model
Our transgenic neuronal p48ZnF bioluminescence mouse model allows the study of higher brain functions in vivo in living mice. Neuron-specific over-expression of p48ZnF in the mouse brain. Differential Response in Transgenic and Wild Type Mice Neurons to Glutamate Stimulation: Current changes across the cell membrane of a single differentiated neuron upon addition of 1 mM…
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p60TRP mouse model
Our transgenic neuronal p60TRP bioluminescence mouse model allows in vivo analysis in living animals. Our transgenic p60TRP mice allow in vivo analysis in living mice to study memory & learning effects, as well as higher brain cognitive functions Neuron-specific over-expression of p60TRP & luciferase in the mouse brain allows us to investigate in vivo in…